A Hydro-elastic Model of Hydrocephalus

نویسندگان

  • A. Smillie
  • I. Sobey
چکیده

We combine elements of poroelasticity and of fluid mechanics to construct a mathematical model of the human brain and ventricular system. The model is used to study hydrocephalus, a pathological condition in which the normal flow of the cerebrospinal fluid is disturbed, causing the brain to become deformed. Our model extends recent work in this area by including flow through the aqueduct, by incorporating boundary conditions which we believe more accurately represent the anatomy of the brain and by including time dependence. This enables us to construct a quantitative model of the onset, development and treatment of this condition. We formulate and solve the governing equations and boundary conditions for this model and give results which are relevant to clinical observations.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The effect of implementing family-centered empowerment model on the empowerment of mothers of children with hydrocephalus.

Introduction: Hydrocephalus, due to the disabilities it causes for children, also causes many problems for their mothers. The present study was conducted to investigate the effect of implementing a family-centered empowerment model on the empowerment of mothers of children with hydrocephalus. Method: In this quasi-experimental study, 60 mothers of children with hydrocephalus participated and we...

متن کامل

Unsteady Magneto Hydro Dynamic Flow of a Second Order Fluid over an Oscillating Sheet with a Second Order Slip Flow Model

Unsteady slip-flow of second grade non-Newtonian electrically conducting fluid over an oscillating sheet has been considered and solved numerically. A second-order slip velocity model is used to predict the flow characteristic past the wall. With the assumption of infinite length in x-direction, velocity of the fluid can be assumed as a function of y and t, hence, with proper variable change pa...

متن کامل

Reassessment of brain elasticity for analysis of biomechanisms of hydrocephalus.

This paper presents results from a finite element study of the biomechanics of hydrocephalus, with special emphasis on a reassessment of the parenchyma elastic modulus. A two-dimensional finite element model of the human brain/ventricular system is developed and analysed under hydrocephalic loading conditions. It is shown that the Young's modulus of the brain parenchyma used in previous studies...

متن کامل

Decompensated chronic congenital hydrocephalus.

A 66 year-old woman with congenital macro cephaly and developmental delay presented with aphasia and right-sided weakness. Head CT revealed severe hydrocephalus of the lateral and third ventricles with a normal fourth ventricle due to a chronic congenital process (Fig. 1A). MRI confirmed subacute embolic infarcts of the left middle cerebral artery territory (Fig. 1B) and a heparin drip was init...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2004